Doctors are being urged to reconsider a planned three-day strike with the government of the largest health system in the nation warning the job walk-off will put patient safety at risk.

NSW Health Minister Ryan Park said the Australian Salaried Medical Officers Federation's industrial action starting on Tuesday would be in breach of Industrial Relations Commission orders to cease organised labour actions for the next three months.

The knock-on effect would disrupt already strained emergency departments with surgeries inevitably to be delayed, he said.

"ASMOF's strike plans will disrupt our hospitals and health facilities across NSW - both to emergency departments as well as planned surgeries - contrary to the union's claims patient care will not be impacted," Mr Park said on Monday.

"It is inexplicable ASMOF would actively choose to jeopardise patient safety over resolving its claim in the IRC.

"I say to ASMOF, it is not too late to return to the IRC."

The minister urged doctors to accept a deal with three per cent backpay to July and allow negotiations for a broader agreement by calling off the strike.

He said the government had been negotiating with several unions of various professions in good faith and had delivered pay increases for workers.

The doctors' union said members were being threatened with disciplinary action and regulator referrals for taking industrial action.

"This is a strategically timed attempt to dissuade our members from participating in the campaign without appropriate context," the union's president Nicholas Spooner said in a statement.

The strike will be carried out without compromising patient safety, he insisted.

"If the NSW government were serious about reporting genuine threats to patient safety and welfare, they would have to report themselves for failing to staff our public hospitals safely," Dr Spooner said.

More than 100,000 people are waiting for a procedure in NSW and the wait is expected to lengthen as doctors wage a three-day strike.

Medical indemnity insurers have also cautioned doctors they could face disciplinary action for participating in the strike in defiance of the industrial umpire's orders.

The strike threat is the latest dispute embroiling NSW Health, with nurses also in a prolonged battle with the government that has included going on strike in November.

Psychiatrists are also resigning from public hospitals in droves amid a wage dispute, saying they are not paid enough compared to interstate colleagues and those in private practice.