A report into the much-maligned early operations of the Lady Cilento Children's Hospital in Brisbane found a long list of problems from missing medical records to disoriented staff.
A clinical review team, containing leading public health figures from NSW and Victoria, completed the report following teething problems once the hospital opened last November.
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It focused on the first two weeks of operation after more than 3000 staff and patients from the merged Mater and Royal Children's hospitals moved to the south Brisbane site.
The report found the transition involved "an unprecedented convergence of challenges and complexities" for the hospital but praised staff for their treatment of patients.
The panel said while the serious events led to minimal harm, they did find several cases where the risk of a serious safety event was averted because of the actions of staff or family members.
"Several staff members worked under stressful conditions because they were unfamiliar with the new hospital, its processes and its culture," the report said.
In many cases, medical records were incomplete or missing when they were transferred across to the new facility.
The review found these were caused by staff being unfamiliar with the hospital, incorrect or poorly located equipment, problems in transferring patient notes and issues with new telephone and communication systems.
Children's Health Queensland chair Susan Johnston admitted the move took place "in extraordinarily challenging and complex circumstances", admitting several unexpected problems emerged.
"It was a difficult time and a difficult process but our staff rose to that challenge magnificently," she said.
"One of the clear messages coming from this report is that our staff went above and beyond their normal role descriptions."
Ms Johnston was confident all the issues had since been addressed.
Health Minister Cameron Dick said the report was further evidence the commissioning process administered by the previous Liberal National Party government was flawed.
Mr Dick also said he was confident the hospital was now operating safely.